Abnormal PcG protein expression in Hodgkin's lymphoma. Relation with E2F6 and NFkappaB transcription factors.

M, Sánchez-Beato; E, Sánchez; JF, García; A, Pérez-Rosado; MC, Montoya; M, Fraga; MJ, Artiga; M, Navarrete; V, Abraira; M, Morente; M, Esteller; H, Koseki; M, Vidal; MA, Piris

doi:10.1002/path.1661

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Abnormal PcG protein expression in Hodgkin's lymphoma. Relation with E2F6 and NFkappaB transcription factors.

Shared by NobleBlocks on Dec 1, 2004 • 12:00 AM UTC

Authors:

Sánchez-Beato M

Sánchez E

García JF

Abstract

The Polycomb group (PcG) of proteins comprises a family of repressors of homeobox genes that play key roles in body formation, haematopoiesis and cell cycle control. In this study, a large-scale analysis of PcG protein expression (BMI1, MEL18, PH1, RNF2, RING1, and RYBP) was performed in 321 Hodgkin...

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