Abnormal PcG protein expression in Hodgkin's lymphoma. Relation with E2F6 and NFκB transcription factors

Sánchez‐Beato, Margarita; Sánchez, Esther; F. Garcı́a, Juan; Pérez‐Rosado, Alberto; C. Montoya, Marı́a; F. Fraga, Mario; J. Artiga, María; Navarrete, Mercedes; Abraira, Víctor; M. Morente, Manuel; Esteller, Manel; Koseki, Haruhiko; Vidal, Miguel; Á. Piris, Miguel

doi:10.1002/path.1661

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Abnormal PcG protein expression in Hodgkin's lymphoma. Relation with E2F6 and NFκB transcription factors

Published in The Journal of Pathology • Oct 7, 2004

Authors:

Margarita Sánchez‐Beato

Esther Sánchez

Juan F. Garcı́a

Abstract

The Polycomb group (PcG) of proteins comprises a family of repressors of homeobox genes that play key roles in body formation, haematopoiesis and cell cycle control. In this study, a large-scale analysis of PcG protein expression (BMI1, MEL18, PH1, RNF2, RING1, and RYBP) was performed in 321 Hodgkin...

Subject

BMI1

Transcription factor

Polycomb-group proteins

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