The Prospective, Observational, Multicenter, Major Trauma Transfusion (PROMMTT) Study

B. Holcomb, John; J. del Junco, Deborah; E. Fox, Erin; E. Wade, Charles; J. Cohen, Mitchell; A. Schreiber, Martin; H. Alarcon, Louis; Bai, Yu; J. Brasel, Karen; M. Bulger, Eileen; A. Cotton, Bryan; Matijevic, Nena; Muskat, Peter; G. Myers, John; A. Phelan, Herb; E. White, Christopher; Zhang, Jiajie; H. Rahbar, Mohammad; the PROMMTT Study Group, for

doi:10.1001/2013.jamasurg.387

Public

The Prospective, Observational, Multicenter, Major Trauma Transfusion (PROMMTT) Study

Published in JAMA Surgery • Oct 15, 2012

Authors:

John B. Holcomb

Deborah J. del Junco

Erin E. Fox

Abstract

OBJECTIVE: To relate in-hospital mortality to early transfusion of plasma and/or platelets and to time-varying plasma:red blood cell (RBC) and platelet:RBC ratios. DESIGN: Prospective cohort study documenting the timing of transfusions during active resuscitation and patient outcomes. Data were anal...

Subject

Medicine

Hazard ratio

Platelet

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