Phases of Aβ-deposition in the human brain and its relevance for the development of AD

Rudolf Thal, Dietmar; Rüb, Udo; Orantes, M; Braak, Heiko

doi:10.1212/wnl.58.12.1791

Public

Phases of Aβ-deposition in the human brain and its relevance for the development of AD

Published in Neurology • Jun 25, 2002

Authors:

Dietmar Rudolf Thal

Udo Rüb

M Orantes

Abstract

BACKGROUND: The deposition of the amyloid beta protein (Abeta) is a histopathologic hallmark of AD. The regions of the medial temporal lobe (MTL) are hierarchically involved in Abeta-deposition. OBJECTIVE: To clarify whether there is a hierarchical involvement of the regions of the entire brain as w...

Subject

Brainstem

Pathology

Neocortex

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