Early postinduction intensification therapy improves survival for children and adolescents with high-risk acute lymphoblastic leukemia: a report from the Children's Oncology Group

L. Seibel, Nita; G. Steinherz, Peter; N. Sather, Harland; B. Nachman, James; DeLaat, Cynthia; J. Ettinger, Lawrence; R. Freyer, David; A. Mattano, Leonard; A. Hastings, Caroline; M. Rubin, Charles; Bertolone, Kathy; Franklin, Janet; A. Heerema, Nyla; L. Mitchell, Torrey; F. Pyesmany, Allan; La, Mei; Edens, Cheryl; S. Gaynon, Paul

doi:10.1182/blood-2007-02-070342

Public

Early postinduction intensification therapy improves survival for children and adolescents with high-risk acute lymphoblastic leukemia: a report from the Children's Oncology Group

Published in Blood • Nov 27, 2007

Authors:

Nita L. Seibel

Peter G. Steinherz

Harland N. Sather

Abstract

Longer and more intensive postinduction intensification (PII) improved the outcome of children and adolescents with "higher risk" acute lymphoblastic leukemia (ALL) and a slow marrow response to induction therapy. In the Children's Cancer Group study (CCG-1961), we tested longer versus more intensiv...

Subject

Medicine

Lymphoblastic Leukemia

Pediatrics

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