Modular Variations of the Human Major Histocompatibility Complex Class III Genes for Serine/Threonine Kinase RP, Complement Component C4, Steroid 21-Hydroxylase CYP21, and Tenascin TNX (the RCCX Module)

Yang, Zhenyu; R. Mendoza, Anna; R. Welch, Thomas; B. Zipf, William; Yung Yu, C.

doi:10.1074/jbc.274.17.12147

Public

Modular Variations of the Human Major Histocompatibility Complex Class III Genes for Serine/Threonine Kinase RP, Complement Component C4, Steroid 21-Hydroxylase CYP21, and Tenascin TNX (the RCCX Module)

Published in Journal of Biological Chemistry • Apr 1, 1999

Authors:

Zhenyu Yang

Anna R. Mendoza

Thomas R. Welch

Abstract

The frequent variations of human complement component C4 gene size and gene numbers, plus the extensive polymorphism of the proteins, render C4 an excellent marker for major histocompatibility complex disease associations. As shown by definitive RFLPs, the tandemly arranged genes RP, C4, CYP21, and ...

Subject

Genetics

Biology

Pseudogene

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!