An Improved Model for Disease Progression in Patients From the Alzheimer's Disease Neuroimaging Initiative

N. Samtani, Mahesh; Farnum, Michael; S. Lobanov, Victor; Yang, Eric; Raghavan, Nandini; DiBernardo, Allitia; A. Narayan, Vaibhav; the Alzheimer's Disease Neuroimaging Initiative, And

doi:10.1177/0091270011405497

Public

An Improved Model for Disease Progression in Patients From the Alzheimer's Disease Neuroimaging Initiative

Published in The Journal of Clinical Pharmacology • Jun 10, 2011

Authors:

Mahesh N. Samtani

Michael Farnum

Victor S. Lobanov

Abstract

The objective of this analysis was to develop a semi-mechanistic nonlinear disease progression model using an expanded set of covariates that captures the longitudinal change of Alzheimer's Disease Assessment Scale (ADAS-cog) scores from the Alzheimer's Disease Neuroimaging Initiative study that con...

Subject

Neuroimaging

Alzheimer's Disease Neuroimaging Initiative

Disease

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