Genetic and biochemical analyses of the <i>Pseudomonas aeruginosa</i> Psl exopolysaccharide reveal overlapping roles for polysaccharide synthesis enzymes in Psl and LPS production

S. Byrd, Matthew; Sadovskaya, Irina; Vinogradov, Evgueny; Lu, Haiping; B. Sprinkle, April; H. Richardson, Stephen; Ma, Luyan; Ralston, Brad; R. Parsek, Matthew; M. Anderson, Erin; S. Lam, Joseph; J. Wozniak, Daniel

doi:10.1111/j.1365-2958.2009.06795.x

Public

Genetic and biochemical analyses of the Pseudomonas aeruginosa Psl exopolysaccharide reveal overlapping roles for polysaccharide synthesis enzymes in Psl and LPS production

Shared by NobleBlocks on Aug 1, 2009 • 12:00 AM UTC

Authors:

Matthew S. Byrd

Irina Sadovskaya

Evgueny Vinogradov

Abstract

Summary Exopolysaccharides contribute significantly to attachment and biofilm formation in the opportunisitc pathogen Pseudomonas aeruginosa . The Psl polysaccharide, which is synthesized by the p olysaccharide s ynthesis l ocus ( psl ), is required for biofilm formation in non‐mucoid strains that d...

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