Inhibition of Ethanol-Induced Liver Disease in the Intragastric Feeding Rat Model by Chlormethiazole

Gouillon, Z.‐Q.; Lucas, Danièle; Li, J.; Hagbjörk, A.-L.; French, B.A.; Fu, Paul; Fang, Chuling; Ingelman‐Sundberg, Magnus; M. Donohue, Terrence; W. French, Samuel

doi:10.1046/j.1525-1373.2000.22435.x

Public

Inhibition of Ethanol-Induced Liver Disease in the Intragastric Feeding Rat Model by Chlormethiazole

Published in Proceedings of The Society for Experimental Biology and Medicine • Sep 1, 2000

Authors:

Z.‐Q. Gouillon

Danièle Lucas

J. Li

Abstract

The purpose of this investigation was to assess the effect of chlormethiazole treatment on liver damage in the experimental rat intragastric ethanol-feeding model of alcoholic liver disease. Chlormethiazole has been used in the treatment of alcoholic withdrawal and has been shown to inhibit cytochro...

Subject

CYP2E1

Chlorzoxazone

Ethanol

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