AfroDb: A Select Highly Potent and Diverse Natural Product Library from African Medicinal Plants

Ntie‐Kang, Fidele; Zofou, Dénis; B. Babiaka, Smith; Meudom, Rolande; Scharfe, Michael; L. Lifongo, Lydia; A. Mbah, James; Meva’a Mbaze, Luc; Sippl, Wolfgang; M. N. Efange, Simon

doi:10.1371/journal.pone.0078085

Public

AfroDb: A Select Highly Potent and Diverse Natural Product Library from African Medicinal Plants

Published in PLoS ONE • Oct 30, 2013

Authors:

Fidele Ntie‐Kang

Dénis Zofou

Smith B. Babiaka

Abstract

Computer-aided drug design (CADD) often involves virtual screening (VS) of large compound datasets and the availability of such is vital for drug discovery protocols. We assess the bioactivity and "drug-likeness" of a relatively small but structurally diverse dataset (containing >1,000 compounds) fr...

Subject

Lipinski's rule of five

Natural product

Drug discovery

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