Safety and Efficacy of Tigecycline in Treatment of Skin and Skin Structure Infections: Results of a Double-Blind Phase 3 Comparison Study with Vancomycin-Aztreonam

Breedt, Johannes; Teras, Jüri; Gardovskis, Jānis; Maritz, Frans; Vaasna, T.; Patrick Ross, Douglas; Gioud-Paquet, Martine; Dartois, Nathalie; J. Ellis‐Grosse, Evelyn; Loh, Evan

doi:10.1128/aac.49.11.4658-4666.2005

Public

Safety and Efficacy of Tigecycline in Treatment of Skin and Skin Structure Infections: Results of a Double-Blind Phase 3 Comparison Study with Vancomycin-Aztreonam

Published in Antimicrobial Agents and Chemotherapy • Oct 26, 2005

Authors:

Johannes Breedt

Jüri Teras

Jānis Gardovskis

Abstract

In a randomized, double-blind, controlled trial, 546 patients with complicated skin and skin structure infections received tigecycline 100 mg/day (a 100-mg initial dose and then 50 mg intravenously twice daily) or the combination of vancomycin 2 g/day (1 g intravenously twice daily) and aztreonam 4 ...

Subject

Tigecycline

Medicine

Aztreonam

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