Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions.

SI, Hung; WH, Chung; SH, Jee; WC, Chen; YT, Chang; WR, Lee; SL, Hu; MT, Wu; GS, Chen; TW, Wong; PF, Hsiao; WH, Chen; HY, Shih; WH, Fang; CY, Wei; YH, Lou; YL, Huang; JJ, Lin; YT, Chen

doi:10.1097/01.fpc.0000199500.46842.4a

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Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions.

Shared by NobleBlocks on Apr 1, 2006 • 12:00 AM UTC

Authors:

Hung SI

Chung WH

Jee SH

Abstract

The anticonvulsant carbamazepine (CBZ) frequently causes cutaneous adverse drug reactions (cADRs), including maculopapular eruption (MPE), hypersensitivity syndrome (HSS), Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). We reported that SJS/TEN caused by CBZ is strongly associat...

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