Transcriptome Analysis Reveals Markers of Aberrantly Activated Innate Immunity in Vitiligo Lesional and Non-Lesional Skin

Yu, Richard; Broady, Raewyn; Huang, Yuanshen; Wang, Yang; Yu, Jie; Gao, Min; K. Levings, Megan; Wei, Shencai; Zhang, Shengquan; Xu, Aie; Su, Mingwan; Dutz, Jan; Zhang, Xuejun; Zhou, Youwen

doi:10.1371/journal.pone.0051040

Public

Transcriptome Analysis Reveals Markers of Aberrantly Activated Innate Immunity in Vitiligo Lesional and Non-Lesional Skin

Published in PLoS ONE • Dec 10, 2012

Authors:

Richard Yu

Raewyn Broady

Yuanshen Huang

Abstract

BACKGROUND: Vitiligo is characterized by the death of melanocytes in the skin. This is associated with the presence of T cell infiltrates in the lesional borders. However, at present, there is no detailed and systematic characterization on whether additional cellular or molecular changes are present...

Subject

Vitiligo

Innate immune system

Transcriptome

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