Prospective, Randomized, Multicenter, Controlled Trial of a Bioartificial Liver in Treating Acute Liver Failure

A. Demetriou, Achilles; S. Brown, Robert; W. Busuttil, Ronald; H. Fair, Jeffrey; M. McGuire, Brendan; Rosenthal, Philip; Schulte Am Esch, Jan; Lerut, Jan; L. Nyberg, Scott; Salizzoni, Mauro; A. Fagan, Elizabeth; de Hemptinne, Bernard; E. Broelsch, Christoph; Muraca, Maurizio; Manuel Salmerón, Joan; M. Rabkin, John; J. Metselaar, Herold; S. Pratt, Daniel; de la Mata, Manuel; McChesney, Lawrence; T. Everson, Gregory; T. Lavin, Philip; C. Stevens, Anthony; Pitkin, Zorina; A. Solomon, Barry

doi:10.1097/01.sla.0000124298.74199.e5

Public

Prospective, Randomized, Multicenter, Controlled Trial of a Bioartificial Liver in Treating Acute Liver Failure

Published in Annals of Surgery • Apr 12, 2004

Authors:

Achilles A. Demetriou

Robert S. Brown

Ronald W. Busuttil

Abstract

In Brief Objective: The HepatAssist liver support system is an extracorporeal porcine hepatocyte-based bioartificial liver (BAL). The safety and efficacy of the BAL were evaluated in a prospective, randomized, controlled, multicenter trial in patients with severe acute liver failure. Summary Backgro...

Subject

Medicine

Fulminant hepatic failure

Internal medicine

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