Whole-Genome Random Sequencing and Assembly of <i>Haemophilus influenzae</i> Rd

Fleischmann, Robert; D. Adams, Mark; White, Owen; A. Clayton, Rebecca; F. Kirkness, Ewen; R. Kerlavage, Anthony; J. Bult, Carol; Tomb, Jean-François; Dougherty, Brian; M. Merrick, Joseph; McKenney, Keith; Sutton, Granger; FitzHugh, Will; Fields, Chris; D. Gocayne, Jeannine; Scott, John; B. Shirley, Robert; Liu, Li-lng; Glodek, Anna; M. Kelley, Jenny; F. Weidman, Janice; A. Phillips, Cheryl; Spriggs, Tracy; Hedblom, Eva; Cotton, Matthew; R. Utterback, Teresa; C. Hanna, Michael; T. Nguyen, David; M. Saudek, Deborah; Brandon, Rhonda; D. Fine, Leah; L. Fritchman, Janice; L. Fuhrmann, Joyce; S. M. Geoghagen, N.; L. Gnehm, Cheryl; McDonald, Lisa; V. Small, Keith; M. Fraser, Claire; O. Smith, Hamilton; Craig Venter, J.

doi:10.1126/science.7542800

Public

Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd

Published in Science • Jul 28, 1995

Authors:

Robert Fleischmann

Mark D. Adams

Owen White

Abstract

An approach for genome analysis based on sequencing and assembly of unselected pieces of DNA from the whole chromosome has been applied to obtain the complete nucleotide sequence (1,830,137 base pairs) of the genome from the bacterium Haemophilus influenzae Rd. This approach eliminates the need for ...

Subject

Genome

Whole genome sequencing

Biology

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