Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins

A. Tishkoff, Sarah; Dietzsch, E.; C. Speed, William; Pakstis, A.J.; Kidd, J.R.; Cheung, Kei‐Hoi; Bonné‐Tamir, Batsheva; Silvana Santachiara‐Benerecetti, A.; Moral, Pedro; Krings, Matthias; Pääbo, Svante; Watson, Elizabeth; Risch, Neil; Jenkins, T; K. Kídd, Kenneth

doi:10.1126/science.271.5254.1380

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Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins

Published in Science • Mar 8, 1996

Authors:

Sarah A. Tishkoff

E. Dietzsch

William C. Speed

Abstract

Haplotypes consisting of alleles at a short tandem repeat polymorphism (STRP) and an Alu deletion polymorphism at the CD4 locus on chromosome 12 were analyzed in more than 1600 individuals sampled from 42 geographically dispersed populations (13 African, 2 Middle Eastern, 7 European, 9 Asian, 3 Paci...

Subject

Haplotype

Linkage disequilibrium

Alu element

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