Broad usage spectrum of G protein-coupled receptors as coreceptors by primary isolates of HIV.

N, Shimizu; A, Tanaka; A, Oue; T, Mori; T, Ohtsuki; C, Apichartpiyakul; H, Uchiumi; Y, Nojima; H, Hoshino

doi:10.1097/qad.0b013e328326cc0d

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Broad usage spectrum of G protein-coupled receptors as coreceptors by primary isolates of HIV.

Shared by NobleBlocks on Apr 1, 2009 • 12:00 AM UTC

Authors:

Shimizu N

Tanaka A

Oue A

Abstract

Objective HIV-1 can use various G protein-coupled receptors (GPCRs) in addition to CCR5 and CXCR4 as coreceptors; however, this type of HIV-1 infection has hardly been detected in vivo. The objective of this study was to elucidate the spectrum of GPCR usage by HIV-1 populations in vivo.Design CD4-ex...

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