Ionic Mechanisms of Neuronal Excitation by Inhibitory GABA
            <sub>A</sub>
            Receptors

J. Staley, Kevin; L. Soldo, Brandi; R. Proctor, William

doi:10.1126/science.7638623

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Ionic Mechanisms of Neuronal Excitation by Inhibitory GABA A Receptors

Shared by NobleBlocks on Aug 18, 1995 • 12:00 AM UTC

Authors:

Kevin J. Staley

Brandi L. Soldo

William R. Proctor

Abstract

Gamma-aminobutyric acid A (GABA A ) receptors are the principal mediators of synaptic inhibition, and yet when intensely activated, dendritic GABA A receptors excite rather than inhibit neurons. The membrane depolarization mediated by GABA A receptors is a result of the differential, activity-depend...

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