Heat-sensitive TRPV channels in retinal pigment epithelial cells: regulation of VEGF-A secretion.

S, Cordeiro; S, Seyler; J, Stindl; VM, Milenkovic; O, Strauss

doi:10.1167/iovs.09-4720

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Heat-sensitive TRPV channels in retinal pigment epithelial cells: regulation of VEGF-A secretion.

Shared by NobleBlocks on Jun 10, 2010 • 12:00 AM UTC

Authors:

Cordeiro S

Seyler S

Stindl J

Abstract

Purpose Choroidal neovascularization in age-related macular degeneration is caused, to a large extent, by increased secretion of vascular endothelial growth factor (VEGF)-A by the retinal pigment epithelium (RPE). The purpose of the study was to identify pathways that lead to increased VEGF secretio...

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