Heat-Sensitive TRPV Channels in Retinal Pigment Epithelial Cells: Regulation of VEGF-A Secretion

PURPOSE: Choroidal neovascularization in age-related macular degeneration is caused, to a large extent, by increased secretion of vascular endothelial growth factor (VEGF)-A by the retinal pigment epithelium (RPE). The purpose of the study was to identify pathways that lead to increased VEGF secreti... View More