High expression of Toll-like receptor 4/myeloid differentiation factor 88 signals correlates with poor prognosis in colorectal cancer

L Wang, E; Rong Qian, Zhi; Nakasono, Masahiko; Tanahashi, Toshihito; Yoshimoto, Katsuhiko; Bando, Yoshiyuki; Kudo, Eiji; Shimada, Mitsuo; Sano, Toshiaki

doi:10.1038/sj.bjc.6605558

Public

High expression of Toll-like receptor 4/myeloid differentiation factor 88 signals correlates with poor prognosis in colorectal cancer

Published in British Journal of Cancer • Feb 9, 2010

Authors:

E L Wang

Zhi Rong Qian

Masahiko Nakasono

Abstract

BACKGROUND: The Toll-like receptor (TLR) 4 signalling pathway has been shown to have oncogenic effects in vitro and in vivo. To demonstrate the role of TLR4 signalling in colon tumourigenesis, we examined the expression of TLR4 and myeloid differentiation factor 88 (MyD88) in colorectal cancer (CRC)...

Subject

Colorectal cancer

Hazard ratio

Medicine

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