Lactobacillus plantarum MB452 enhances the function of the intestinal barrier by increasing the expression levels of genes involved in tight junction formation

C. Anderson, Rachel; L. Cookson, Adrian; C. McNabb, Warren; Park, Zaneta; J. McCann, Mark; J. Kelly, William; C. Roy, Nicole

doi:10.1186/1471-2180-10-316

Public

Lactobacillus plantarum MB452 enhances the function of the intestinal barrier by increasing the expression levels of genes involved in tight junction formation

Published in BMC Microbiology • Jan 1, 2010

Authors:

Rachel C. Anderson

Adrian L. Cookson

Warren C. McNabb

Abstract

BACKGROUND: Intestinal barrier function is important for preserving health, as a compromised barrier allows antigen entry and can induce inflammatory diseases. Probiotic bacteria can play a role in enhancing intestinal barrier function; however, the mechanisms are not fully understood. Existing stud...

Subject

Tight junction

Barrier function

Lactobacillus plantarum

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