Prospective clinical evaluation of a LightCycler-mediated polymerase chain reaction assay, a nested-PCR assay and a galactomannan enzyme-linked immunosorbent assay for detection of invasive aspergillosis in neutropenic cancer patients and haematological stem cell transplant recipients.

D, Buchheidt; M, Hummel; D, Schleiermacher; B, Spiess; R, Schwerdtfeger; OA, Cornely; S, Wilhelm; S, Reuter; W, Kern; T, Südhoff; H, Mörz; R, Hehlmann

doi:10.1111/j.1365-2141.2004.04904.x

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Prospective clinical evaluation of a LightCycler-mediated polymerase chain reaction assay, a nested-PCR assay and a galactomannan enzyme-linked immunosorbent assay for detection of invasive aspergillosis in neutropenic cancer patients and haematological stem cell transplant recipients.

Shared by NobleBlocks on Apr 1, 2004 • 12:00 AM UTC

Authors:

Buchheidt D

Hummel M

Schleiermacher D

Abstract

Invasive aspergillosis (IA) is a considerable clinical problem in neutropenic patients with haematological malignancies but its diagnosis remains difficult. We prospectively evaluated a LightCycler polymerase chain reaction (PCR) assay, a nested-PCR assay and a galactomannan (GM) enzyme-linked immun...

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