Role of cannabinoid CB1 receptors and tumor necrosis factor‐α in the gut and systemic anti‐inflammatory activity of SR 141716 (Rimonabant) in rodents

Croci, Tiziano; Landi, Marco; Galzin, Anne‐Marie; Marini, Pietro

doi:10.1038/sj.bjp.0705412

Public

Role of cannabinoid CB1 receptors and tumor necrosis factor‐α in the gut and systemic anti‐inflammatory activity of SR 141716 (Rimonabant) in rodents

Published in British Journal of Pharmacology • Sep 1, 2003

Authors:

Tiziano Croci

Marco Landi

Anne‐Marie Galzin

Abstract

(1) We investigated the effect of the cannabinoid CB1 receptor antagonist, SR 141716, on indomethacin-induced small intestine inflammation and Escherichia coli lipopolysaccharide (LPS)-induced plasma TNF-alpha (TNF) release in comparison to the cannabinoid CB2 receptor antagonist, SR 144528, in rode...

Subject

Cannabinoid receptor

Cannabinoid

Tumor necrosis factor alpha

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