Changes in renal function associated with oral emtricitabine/tenofovir disoproxil fumarate use for HIV pre-exposure prophylaxis

Solomon, Marc; R. Lama, Javier; V. Glidden, David; Mulligan, Kathleen; McMahan, Vanessa; Liu, Albert; V. Guanira, Juan; G. Veloso, Valdiléa; H. Mayer, Kenneth; Chariyalertsak, Suwat; Schechter, Mauro; Bekker, Linda‐Gail; G. Kallás, Esper; Burns, David; M. Grant, Robert

doi:10.1097/qad.0000000000000156

Public

Changes in renal function associated with oral emtricitabine/tenofovir disoproxil fumarate use for HIV pre-exposure prophylaxis

Published in AIDS • Feb 5, 2014

Authors:

Marc Solomon

Javier R. Lama

David V. Glidden

Abstract

OBJECTIVE: Tenofovir disoproxil fumarate (TDF) pre-exposure prophylaxis decreases sexual acquisition of HIV infection. We sought to evaluate the renal safety of TDF in HIV-uninfected persons. DESIGN AND METHODS: The Iniciativa Profilaxis Pre-Exposición (iPrEx) study randomly assigned 2499 HIV-serone...

Subject

Emtricitabine

Pre-exposure prophylaxis

Medicine

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