Gene–environment interactions in asthma and allergy: the end of the beginning?

Vercelli, Donata

doi:10.1097/aci.0b013e32833653d7

Public

Gene–environment interactions in asthma and allergy: the end of the beginning?

Published in Current Opinion in Allergy and Clinical Immunology • Mar 2, 2010

Authors:

Donata Vercelli

Abstract

PURPOSE OF REVIEW: The pathogenesis of asthma and allergy typically involves not only distinct genetic and environmental factors, but also interactions between the two. Innate-immunity genes [particularly CD14, toll-like receptor (TLR)4 and TLR2, the critical mediators of responses to bacteria in th...

Subject

Asthma

Innate immune system

Immunology

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