Bioavailability of interferon beta 1b in MS patients with and without neutralizing antibodies

Deisenhammer, Florian; Reindl, Markus; Harvey, Jennifer; Gasse, T.; Dilitz, Erika; Berger, Thomas

doi:10.1212/wnl.52.6.1239

Public

Bioavailability of interferon beta 1b in MS patients with and without neutralizing antibodies

Published in Neurology • Apr 1, 1999

Authors:

Florian Deisenhammer

Markus Reindl

Jennifer Harvey

Abstract

BACKGROUND: Neutralizing antibodies (NAB) to interferon beta (IFNbeta) occur in about one-third of MS patients treated with IFNbeta-1b and there is an association with a loss of clinical and MRI efficacy. However, there are no data regarding the bioavailability of IFNbeta-1b in patients with and wit...

Subject

Titer

Antibody

Bioavailability

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