Bioavailability of interferon beta 1b in MS patients with and without neutralizing antibodies.

F, Deisenhammer; M, Reindl; J, Harvey; T, Gasse; E, Dilitz; T, Berger

doi:10.1212/wnl.52.6.1239

Public

Bioavailability of interferon beta 1b in MS patients with and without neutralizing antibodies.

Shared by NobleBlocks on Apr 1, 1999 • 12:00 AM UTC

Authors:

Deisenhammer F

Reindl M

Harvey J

Abstract

Background Neutralizing antibodies (NAB) to interferon beta (IFNbeta) occur in about one-third of MS patients treated with IFNbeta-1b and there is an association with a loss of clinical and MRI efficacy. However, there are no data regarding the bioavailability of IFNbeta-1b in patients with and with...

Discussions