Heterochromatin protein 1 is recruited to various types of DNA damage

S. Luijsterburg, Martijn; Dinant, Christoffel; Lans, Hannes; Stap, Jan; Wiernasz, Elżbieta; Lagerwerf, Saskia; O. Warmerdam, Daniël; Lindh, Michael; C. Brink, Maartje; Dobrucki, Jurek; A. Aten, Jacob; Fousteri, Maria; Jansen, Gert; P. Dantuma, Nico; Vermeulen, Wim; H.F. Mullenders, Leon; B. Houtsmuller, Adriaan; J. Verschure, Pernette; van Driel, Roel

doi:10.1083/jcb.200810035

Public

Heterochromatin protein 1 is recruited to various types of DNA damage

Published in The Journal of Cell Biology • May 18, 2009

Authors:

Martijn S. Luijsterburg

Christoffel Dinant

Hannes Lans

Abstract

Heterochromatin protein 1 (HP1) family members are chromatin-associated proteins involved in transcription, replication, and chromatin organization. We show that HP1 isoforms HP1-alpha, HP1-beta, and HP1-gamma are recruited to ultraviolet (UV)-induced DNA damage and double-strand breaks (DSBs) in hu...

Subject

Biology

Heterochromatin

DNA

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