The Use of Molecular Profiling to Predict Survival after Chemotherapy for Diffuse Large-B-Cell Lymphoma

Rosenwald, Andreas; W. Wright, George; C. Chan, Wing; M. Connors, Joseph; Campo, Elı́as; I. Fisher, Richard; D. Gascoyne, Randy; K. Müller-Hermelink, H.; B. Smeland, Erlend; M. Giltnane, Jena; M. Hurt, Elaine; Zhao, Hong; Averett, Lauren; Yang, Liming; H. Wilson, Wyndham; S. Jaffe, Elaine; H. Simon, Richard; D. Klausner, Richard; Powell, John; L Duffey, P; L. Longo, Dan; C. Greiner, Timothy; D. Weisenburger, Dennis; G. Sanger, Warren; J. Davé, Bhavana; C. Lynch, James; M. Vose, Julie; O. Armitage, Jamés; Montserrat, Emilio; López‐Guillermo, Armando; M. Grogan, Thomas; P. Miller, Thomas; Leblanc, M.; Ott, German; Kvaløy, Stein; Delabie, Jan; Holte, Harald; Krajči, Peter; Stokke, Trond; M. Staudt, Louis

doi:10.1056/nejmoa012914

Public

The Use of Molecular Profiling to Predict Survival after Chemotherapy for Diffuse Large-B-Cell Lymphoma

Published in New England Journal of Medicine • Jun 20, 2002

Authors:

Andreas Rosenwald

George W. Wright

Wing C. Chan

Abstract

BACKGROUND: The survival of patients with diffuse large-B-cell lymphoma after chemotherapy is influenced by molecular features of the tumors. We used the gene-expression profiles of these lymphomas to develop a molecular predictor of survival. METHODS: Biopsy samples of diffuse large-B-cell lymphoma...

Subject

Lymphoma

Diffuse large B-cell lymphoma

Germinal center

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