Digital Genome-Wide ncRNA Expression, Including SnoRNAs, across 11 Human Tissues Using PolyA-Neutral Amplification

C. Castle, John; D. Armour, Christopher; Löwer, Martin; R. Haynor, David; C. Biery, Matthew; Bouzek, Heather; Chen, Ronghua; D. Jackson, Stuart; M. Johnson, Jason; A. Rohl, Carol; K. Raymond, Christopher

doi:10.1371/journal.pone.0011779

Public

Digital Genome-Wide ncRNA Expression, Including SnoRNAs, across 11 Human Tissues Using PolyA-Neutral Amplification

Published in PLoS ONE • Jul 26, 2010

Authors:

John C. Castle

Christopher D. Armour

Martin Löwer

Abstract

Non-coding RNAs (ncRNAs) are an essential class of molecular species that have been difficult to monitor on high throughput platforms due to frequent lack of polyadenylation. Using a polyadenylation-neutral amplification protocol and next-generation sequencing, we explore ncRNA expression in eleven ...

Subject

Small nucleolar RNA

Biology

Non-coding RNA

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