Clozapine Alone versus Clozapine and Risperidone with Refractory Schizophrenia

G. Honer, William; E. Thornton, Allen; Chen, Eric; C. K. Chan, Raymond; Wong, Jessica; Bergmann, Andrea; Falkai, Peter; Pomarol‐Clotet, Edith; J. McKenna, Peter; Stip, Émmanuel; L. Williams, Richard; William MacEwan, G.; M. Wasan, Kishor; M. Procyshyn, Ric

doi:10.1056/nejmoa053222

Public

Clozapine Alone versus Clozapine and Risperidone with Refractory Schizophrenia

Published in New England Journal of Medicine • Feb 1, 2006

Authors:

William G. Honer

Allen E. Thornton

Eric Chen

Abstract

BACKGROUND: The treatment of schizophrenia with multiple antipsychotic drugs is common, but the benefits and risks are not known. METHODS: In a randomized, double-blind study, we evaluated patients with schizophrenia and a poor response to treatment with clozapine. The patients continued to take clo...

Subject

Risperidone

Placebo

Medicine

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