Resveratrol prevents age-related memory and mood dysfunction with increased hippocampal neurogenesis and microvasculature, and reduced glial activation.

Maheedhar, Kodali,; Vipan K, Parihar,; Bharathi, Hattiangady,; Vikas, Mishra,; Bing, Shuai,; Ashok K, Shetty,

doi:10.1038/srep08075

Public

Resveratrol prevents age-related memory and mood dysfunction with increased hippocampal neurogenesis and microvasculature, and reduced glial activation.

Published in Scientific reports • Jan 28, 2015

Authors:

Kodali, Maheedhar

Parihar, Vipan K

Hattiangady, Bharathi

Abstract

Greatly waned neurogenesis, diminished microvasculature, astrocyte hypertrophy and activated microglia are among the most conspicuous structural changes in the aged hippocampus. Because these alterations can contribute to age-related memory and mood impairments, strategies efficacious for mitigating...

Subject

Aging

Animals

Astrocytes

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