Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma

C. Castle, John; Löewer, Martin; Boegel, Sebastian; de Graaf, Jos; Bender, Christian; D. Tadmor, Arbel; Boisguérin, Valesca; Bukur, Thomas; Sorn, Patrick; Paret, Claudia; Diken, Mustafa; Kreiter, Sebastian; Türeci, Özlem; Şahin, Uğur

doi:10.1186/1471-2164-15-190

Public

Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma

Published in BMC Genomics • Jan 1, 2014

Authors:

John C. Castle

Martin Löewer

Sebastian Boegel

Abstract

BACKGROUND: Tumor models are critical for our understanding of cancer and the development of cancer therapeutics. Here, we present an integrated map of the genome, transcriptome and immunome of an epithelial mouse tumor, the CT26 colon carcinoma cell line. RESULTS: We found that Kras is homozygously...

Subject

Biology

Cancer research

KRAS

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