The Suppressive Effect of Dietary Restriction and Weight Loss in the Obese on the Generation of Reactive Oxygen Species by Leukocytes, Lipid Peroxidation, and Protein Carbonylation1

Dandona, Paresh; Mohanty, Priya; Ghanim, Husam; Aljada, Ahmad; W. Browne, Richard; Hamouda, Wael; Prabhala, Anu; Afzal, Aqeela; Garg, Rajesh

doi:10.1210/jcem.86.1.7150

Public

The Suppressive Effect of Dietary Restriction and Weight Loss in the Obese on the Generation of Reactive Oxygen Species by Leukocytes, Lipid Peroxidation, and Protein Carbonylation1

Published in The Journal of Clinical Endocrinology & Metabolism • Jan 1, 2001

Authors:

Paresh Dandona

Priya Mohanty

Husam Ghanim

Abstract

Increased reactive oxygen species generation by the leukocytes of the obese may be responsible for increased oxidative injury to lipids and proteins and, hence, atherosclerosis. We have investigated whether reactive oxygen species generation by leukocytes and other indexes of oxidative damage in the...

Subject

TBARS

Reactive oxygen species

Thiobarbituric acid

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