Evidence for Antibody-Mediated Injury as a Major Determinant of Late Kidney Allograft Failure

S. Gaston, Robert; Michael Cecka, J.; L Kasiske, Bert; Fieberg, Ann; Leduc, Robert; Cosio, Fernando; Gourishankar, Sita; P. Grande, Joseph; F. Halloran, Philip; G. Hunsicker, Lawrence; B. Mannon, Roslyn; N. Rush, David; J. Matas, Arthur

doi:10.1097/tp.0b013e3181e065de

Public

Evidence for Antibody-Mediated Injury as a Major Determinant of Late Kidney Allograft Failure

Published in Transplantation • May 12, 2010

Authors:

Robert S. Gaston

J. Michael Cecka

Bert L Kasiske

Abstract

BACKGROUND: Late graft failure (LGF) is believed to be the consequence of immunologic and nonimmunologic insults leading to progressive deterioration in kidney function. We studied recipients with new onset late kidney graft dysfunction (n=173) to determine the importance of C4d staining and circula...

Subject

Medicine

Creatinine

Nephrotoxicity

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