Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist

Bresnihan, Barry; Maria Alvaro-Gracia, Jos�; Cobby, Mark; Doherty, Michael; Domljan, Z; Emery, Paul; Nuki, George; Pavelká, Karel; Rau, Rolf; Rozman, Blaž; Watt, Iain; Williams, Bryan; Aitchison, Roger; McCabe, Dorothy; Musikic, Predrag

doi:10.1002/1529-0131(199812)41:12<2196::aid-art15>3.0.co;2-2

Public

Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist

Published in Arthritis & Rheumatism • Dec 1, 1998

Authors:

Barry Bresnihan

Jos� Maria Alvaro-Gracia

Mark Cobby

Abstract

OBJECTIVE: To evaluate the efficacy and safety of interleukin-1 receptor antagonist (IL-1Ra) in patients with rheumatoid arthritis (RA). METHODS: Patients with active and severe RA (disease duration <8 years) were recruited into a 24-week, double-blind, randomized, placebo-controlled, multicenter st...

Subject

Medicine

Rheumatoid arthritis

Erythrocyte sedimentation rate

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