Novel and therapeutic effect of caffeic acid and caffeic acid phenyl ester on hepatocarcinoma cells: complete regression of hepatoma growth and metastasis by dual mechanism

Chung, Tae‐Wook; Moon, Sung‐Kwon; Chang, Young‐Chae; Ko, Jeong‐Heon; Lee, Young‐Choon; Cho, Gun; Kim, Soo‐Hyun; Kim, Jong‐Guk; Kim, Cheorl‐Ho

doi:10.1096/fj.04-2126com

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Novel and therapeutic effect of caffeic acid and caffeic acid phenyl ester on hepatocarcinoma cells: complete regression of hepatoma growth and metastasis by dual mechanism

Shared by NobleBlocks on Nov 1, 2004 • 12:00 AM UTC

Authors:

Tae‐Wook Chung

Sung‐Kwon Moon

Young‐Chae Chang

Abstract

ABSTRACT Our previous studies have clearly shown that the angiogenic enzymes, matrix metalloproteinase (MMP) ‐2/9, are directly involved in human hepatic tumorigenesis and metastasis and suggest that the MMP‐2/9 inhibitors, which have dual inhibitory activi¬ties on enzyme activity and transcription,...

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