Extent and distribution of white matter hyperintensities in normal aging, MCI, and AD

Yoshita, Mitsuhiro; Fletcher, Evan; Harvey, Danielle; Ortega, M; Martinez, Oliver; M. Mungas, D.; Reed, Bruce; S. DeCarli, C.

doi:10.1212/01.wnl.0000249119.95747.1f

Public

Extent and distribution of white matter hyperintensities in normal aging, MCI, and AD

Published in Neurology • Dec 26, 2006

Authors:

Mitsuhiro Yoshita

Evan Fletcher

Danielle Harvey

Abstract

OBJECTIVE: To analyze the extent and spatial distribution of white matter hyperintensities (WMH) in brain regions from cognitively normal older individuals (CN) and patients with mild cognitive impairment (MCI) and Alzheimer disease (AD). METHODS: We studied 26 mild AD, 28 MCI, and 33 CN. MRI analys...

Subject

Hyperintensity

Splenium

Corpus callosum

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