Reward deficiency syndrome: a biogenetic model for the diagnosis and treatment of impulsive, addictive, and compulsive behaviors.

K, Blum; ER, Braverman; JM, Holder; JF, Lubar; VJ, Monastra; D, Miller; JO, Lubar; TJ, Chen; DE, Comings

doi:10.1080/02791072.2000.10736099

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Reward deficiency syndrome: a biogenetic model for the diagnosis and treatment of impulsive, addictive, and compulsive behaviors.

Shared by NobleBlocks on Nov 1, 2000 • 12:00 AM UTC

Authors:

Blum K

Braverman ER

Holder JM

Abstract

The dopaminergic system, and in particular the dopamine D2 receptor, has been implicated in reward mechanisms. The net effect of neurotransmitter interaction at the mesolimbic brain region induces "reward" when dopamine (DA) is released from the neuron at the nucleus accumbens and interacts with a d...

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