Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes

Petrovič, Nataša; B. Waldén, Tomas; G. Shabalina, Irina; A. Timmons, James; Cannon, Barbara; Nedergaard, Jan

doi:10.1074/jbc.m109.053942

Public

Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes

Published in Journal of Biological Chemistry • Dec 23, 2009

Authors:

Nataša Petrovič

Tomas B. Waldén

Irina G. Shabalina

Abstract

The recent insight that brown adipocytes and muscle cells share a common origin and in this respect are distinct from white adipocytes has spurred questions concerning the origin and molecular characteristics of the UCP1-expressing cells observed in classic white adipose tissue depots under certain ...

Subject

PRDM16

Thermogenin

White adipose tissue

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