Non‐Alzheimer‐type pattern of brain cholineacetyltransferase reduction in dominantly inherited olivopontocerebellar atrophy

J. Kish, Stephen; Robitaille, Yves; El‐Awar, Munir; N. Deck, H.; L. Simmons, Jerry; J. Schut, Lawrence; Chang, Li‐Jan; DiStefano, L.; Freedman, Morris

doi:10.1002/ana.410260309

Public

Non‐Alzheimer‐type pattern of brain cholineacetyltransferase reduction in dominantly inherited olivopontocerebellar atrophy

Published in Annals of Neurology • Sep 1, 1989

Authors:

Stephen J. Kish

Yves Robitaille

Munir El‐Awar

Abstract

We recently reported reduced activity of the cholinergic marker enzyme cholineacetyltransferase (ChAT) in several brain regions of patients with dominantly inherited olivopontocerebellar atrophy (OPCA). To document the regional extent of these changes we performed a comprehensive examination of the ...

Subject

Olivopontocerebellar atrophy

Cholinergic

Cerebral cortex

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!