Identification of binding sites for transcription factors NF-kappa B and AP-2 in the promoter region of the human heme oxygenase 1 gene.

Lavrovsky, Yan; L. Schwartzman, Michal; D Levere, R; Kappas, Attallah; G. Abraham, Nader

doi:10.1073/pnas.91.13.5987

Public

Identification of binding sites for transcription factors NF-kappa B and AP-2 in the promoter region of the human heme oxygenase 1 gene.

Published in Proceedings of the National Academy of Sciences • Jun 21, 1994

Authors:

Yan Lavrovsky

Michal L. Schwartzman

R D Levere

Abstract

Heme oxygenase (HO) is the rate-limiting enzyme in heme catabolism and its activity is induced by many agents, including its substrate heme, heavy metals, UV radiation, and other injurious oxidant conditions. We examined the presence of several regulatory elements in the promoter region of the human...

Subject

Molecular biology

Heme

Transcription factor

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!