Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of miR-200c and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma

Oishi, Naoki; R. Kumar, Mia; Roessler, Stéphanie; Ji, Junfang; Forgues, Marshonna; Budhu, Anuradha; Zhao, Xuelian; B. Andersen, Jesper; hai Ye, Qing; Jia, Hu; Qin, Lun; Yamashita, Taro; Goo Woo, Hyun; Jun Kim, Yoon; Kaneko, Shuichi; Tang, Zhao-You; S. Thorgeirsson, Snorri; Wei Wang, Xin

doi:10.1002/hep.25890

Public

Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of miR-200c and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma

Published in Hepatology • Jun 18, 2012

Authors:

Naoki Oishi

Mia R. Kumar

Stéphanie Roessler

Abstract

UNLABELLED: Intrahepatic cholangiocellular carcinoma (ICC) is the second most common type of primary liver cancer. However, its tumor heterogeneity and molecular characteristics are largely unknown. In this study, we conducted transcriptomic profiling of 23 ICC and combined hepatocellular cholangioc...

Subject

Epithelial–mesenchymal transition

Intrahepatic Cholangiocarcinoma

Transcriptome

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