Cardiovascular Events and Intensity of Treatment in Polycythemia Vera

Marchioli, Roberto; Finazzi, Guido; Specchia, Giorgina; Cacciola, Rossella; Cavazzina, Riccardo; Cilloni, Daniela; De Stefano, Valerio; Maria Elli, Elena; Iurlo, Alessandra; Latagliata, Roberto; Lunghi, Francesca; Lunghi, Monia; Maria Marfisi, Rosa; Musto, Pellegrino; Masciulli, Arianna; Musolino, Caterina; Cascavilla, Nicola; Quarta, Giovanni; Luigia Randi, Maria; Rapezzi, Davide; Ruggeri, Marco; Rumi, Elisa; Rita Scortechini, Anna; Santini, Simone; Scarano, Marco; Siragusa, Sergio; Spadea, Antonio; Tieghi, Alessia; Angelucci, Emanuele; Visani, Giuseppe; Maria Vannucchi, Alessandro; Barbui, Tiziano

doi:10.1056/nejmoa1208500

Public

Cardiovascular Events and Intensity of Treatment in Polycythemia Vera

Published in New England Journal of Medicine • Dec 8, 2012

Authors:

Roberto Marchioli

Guido Finazzi

Giorgina Specchia

Abstract

BACKGROUND: Current treatment recommendations for patients with polycythemia vera call for maintaining a hematocrit of less than 45%, but this therapeutic strategy has not been tested in a randomized clinical trial. METHODS: We randomly assigned 365 adults with JAK2-positive polycythemia vera who we...

Subject

Medicine

Polycythemia vera

Intensity (physics)

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