Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern.

E, Enmark; M, Pelto-Huikko; K, Grandien; S, Lagercrantz; J, Lagercrantz; G, Fried; M, Nordenskjöld; JA, Gustafsson

doi:10.1210/jcem.82.12.4470

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Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern.

Shared by NobleBlocks on Dec 1, 1997 • 12:00 AM UTC

Authors:

Enmark E

Pelto-Huikko M

Grandien K

Abstract

The estrogen receptor (ER) is a ligand-activated transcription factor that mediates the effects of the steroid hormone 17 beta-estradiol, in both males and females. Since the isolation and cloning of ER, the consensus has been that only one such receptor exists. The finding of a second subtype of ER...

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