Formation of the Food Vacuole in Plasmodium falciparum: A Potential Role for the 19 kDa Fragment of Merozoite Surface Protein 1 (MSP119)

R. Dluzewski, Anton; T. Ling, Irene; M. Hopkins, John; Grainger, Munira; Margos, Gabriele; H. Mitchell, G.; A. Holder, Anthony; H. Bannister, L.

doi:10.1371/journal.pone.0003085

Public

Formation of the Food Vacuole in Plasmodium falciparum: A Potential Role for the 19 kDa Fragment of Merozoite Surface Protein 1 (MSP119)

Published in PLoS ONE • Aug 28, 2008

Authors:

Anton R. Dluzewski

Irene T. Ling

John M. Hopkins

Abstract

Plasmodium falciparum Merozoite Surface Protein 1 (MSP1) is synthesized during schizogony as a 195-kDa precursor that is processed into four fragments on the parasite surface. Following a second proteolytic cleavage during merozoite invasion of the red blood cell, most of the protein is shed from th...

Subject

Vacuole

Plasmodium falciparum

Merozoite surface protein

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