Histatin-1, a histidine-rich peptide in human saliva, promotes cell-substrate and cell-cell adhesion

Histatins (Hsts) are histidine-rich peptides exclusively present in the saliva of higher primates. In this study, we explored the effects of Hsts on cell-substrate and cell-cell adhesion. Histatin (Hst)-1 caused a significant (>2-fold) increase (EC50 = 1 μM) in the ability of human adherent cells to... View More