Small bowel adenocarcinoma phenotyping, a clinicobiological prognostic study.

Aparicio, T; Svrcek, M; Zaanan, A; Beohou, E; Laforest, A; Afchain, P; Mitry, Emmanuel; Taieb, J; Di Fiore, F; Gornet, J-M; Thirot-Bidault, A; Sobhani, I; Malka, D; Lecomte, T; Locher, C; Bonnetain, F; Laurent-Puig, P

doi:10.1038/bjc.2013.677

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Small bowel adenocarcinoma phenotyping, a clinicobiological prognostic study.

Shared by NobleBlocks on Dec 10, 2013 • 12:00 AM UTC

Authors:

T Aparicio

M Svrcek

A Zaanan

Abstract

BACKGROUND: Small bowel adenocarcinoma (SBA) is a rare tumour with a poor prognosis. Molecular biology data on SBA carcinogenesis are lacking. METHODS: Expression of HER2, β-catenin, p53 and mismatch repair (MMR) protein was assessed by immunohistochemistry. KRAS, V600E BRAF mutations and microsatel...

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