Small bowel adenocarcinoma phenotyping, a clinicobiological prognostic study

Aparicio, Thomas; Svrcek, M.; Zaanan, Aziz; Beohou, Eric; Laforest, A.; Afchain, Pauline; Mitry, Emmanuel; Taı̈eb, Julien; Di Fiore, F.; Gornet, J-M; Thirot‐Bidault, Anne; Sobhani, Iradj; Malka, David; Lecomte, Thierry; Locher, C.; Bonnetain, Franck; Laurent‐Puig, Pierre

doi:10.1038/bjc.2013.677

Public

Small bowel adenocarcinoma phenotyping, a clinicobiological prognostic study

Published in British Journal of Cancer • Nov 5, 2013

Authors:

Thomas Aparicio

M. Svrcek

Aziz Zaanan

Abstract

BACKGROUND: Small bowel adenocarcinoma (SBA) is a rare tumour with a poor prognosis. Molecular biology data on SBA carcinogenesis are lacking. METHODS: Expression of HER2, β-catenin, p53 and mismatch repair (MMR) protein was assessed by immunohistochemistry. KRAS, V600E BRAF mutations and microsatel...

Subject

KRAS

Microsatellite instability

Internal medicine

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