Toll‐like receptor expression in murine DC subsets: lack of TLR7 expression by CD8α
                    <sup>+</sup>
                    DC correlates with unresponsiveness to imidazoquinolines

D. Edwards, Alexander; S. Diebold, Sandra; M. C. Slack, Emma; Tomizawa, Hideyuki; Hemmi, Hiroaki; Kaisho, Tsuneyasu; Akira, Shizuo; Reis e Sousa, Caetano

doi:10.1002/eji.200323797

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Toll‐like receptor expression in murine DC subsets: lack of TLR7 expression by CD8α + DC correlates with unresponsiveness to imidazoquinolines

Shared by NobleBlocks on Mar 7, 2003 • 12:00 AM UTC

Authors:

Alexander D. Edwards

Sandra S. Diebold

Emma M. C. Slack

Abstract

Abstract Toll‐like receptors (TLR) recognize microbial and viral patterns and activate dendritic cells (DC). TLR distribution among human DC subsets is heterogeneous: plasmacytoid DC (PDC) express TLR1, 7 and 9, while other DC types do not express TLR9 but express other TLR. Here, we report that mRN...

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