The zebrafish reference genome sequence and its relationship to the human genome

Howe, Kerstin; D. Clark, Matthew; Torroja, Carlos; Torrance, James; Berthelot, Camille; Muffato, Matthieu; Collins, John; Humphray, Sean; McLaren, Karen; Matthews, Lucy; McLaren, Stuart; Sealy, Ian; Cáccamo, Mario; Churcher, Carol; Scott, Carol; C. Barrett, Jeffrey; Koch, Romke; Rauch, Gerd-Jörg; White, Simon; Chow, William; Kilian, Britt; Quintais, Leonor; Afonso Guerra‐Assunção, José; Zhou, Yi; Gu, Yong; Yen, Jennifer; Vogel, Jan-Hinnerk; A. Eyre, T.; Redmond, Seth; Banerjee, Ruby; Chi, Jianxiang; Fu, Beiyuan; Langley, Elizabeth; Maguire, Sean; K. Laird, Gavin; Lloyd, David; Kenyon, Emma; Donaldson, Sarah; Sehra, Harminder; P. Almeida, J.; Loveland, Jane; J. Trevanion, Stephen; Jones, Matt; Quail, Mike; Willey, Dave; Hunt, Adrienne; H. Burton, John; Sims, Sarah; McLay, Kirsten; Plumb, Bob; Davis, Joy; M. Clee, Chris; Oliver, Karen; Clark, Richard; Riddle, Clare; Elliott, David; Threadgold, Glen; Harden, Glenn; Ware, Darren; Begum, Sharmin; Mortimore, Beverley; Kerry, Giselle; D. Heath, P.; Phillimore, Benjamin; Tracey, Alan; Corby, N.; Dunn, Matthew; M. Johnson, Christopher; Wood, Jonathan; Clark, Susan; Pelan, Sarah; Griffiths, Guy; Smith, Michelle; Glithero, Rebecca; Howden, Philip; Barker, Nicholas; Lloyd, Christine; Stevens, Christopher; Harley, Joanna; Holt, Karen; Panagiotidis, Georgios; Lovell, J.; Beasley, Helen; Henderson, Carl; Gordon, Daria; A. Auger, Katherine; Wright, Deborah; Collins, Joanna; Raisen, Claire; Dyer, Lauren; Leung, Kenric; Robertson, Lauren; Ambridge, Kirsty; Leongamornlert, Daniel; McGuire, Sarah; Gilderthorp, Ruth; Griffiths, Chris; Manthravadi, Deepa; Nichol, Sarah; Barker, Gary; Whitehead, Siobhan; Kay, Mike; Brown, Jacqueline; Murnane, Clare; Gray, Emma; Humphries, Matthew; Sycamore, Neil; Barker, Darren; Saunders, David; M. Wallis, J.; Babbage, Anne; Hammond, Sian; Mashreghi-Mohammadi, M.; Barr, Lucy; Martin, Sancha; Wray, Paul; Ellington, Andrew; Matthews, Nicholas; Ellwood, Matthew; Woodmansey, Rebecca; Clark, Graham; D. Cooper, James; Tromans, A.; Grafham, Darren; D. Skuce, C.; Pandian, Richard; Andrews, Robert; Harrison, Elliot; Kimberley, Andrew; Garnett, J.; Fosker, Nigel; E. Hall, R.; Garner, P.; Kelly, Daniel; Bird, Christine; Palmer, Sophie; Gehring, Ines; Berger, Andrea; M. Dooley, Christopher; Ersan-Ürün, Zübeyde; Eser, Cigdem; Geiger, Horst; Geisler, Maria; Karotki, Lena; Kirn, A; Konantz, Judith; Konantz, Martina; Oberländer, Martina; Rudolph-Geiger, Silke; Teucke, Mathias; Lanz, Christa; Raddatz, Günter; Osoegawa, Kazutoyo; Zhu, Baoli; Rapp, Amanda; Widaa, Sara; Langford, Cordelia; Yang, Fengtang; C. Schuster, Stephan; P. Carter, Nigel; Harrow, Jennifer; Ning, Zemin; Herrero, Javier; Searle, Steve; J. Enright, Anton; Geisler, Robert; H.A. Plasterk, Ronald; Lee, Charles; Westerfield, Monte; J. de Jong, Pieter; I. Zon, Leonard; H. Postlethwait, John; Nüsslein‐Volhard, Christiane; Hubbard, Tim; Roest Crollius, Hugues; Rogers, Jane; L. Stemple, Derek

doi:10.1038/nature12111

Public

The zebrafish reference genome sequence and its relationship to the human genome

Published in Nature • Apr 16, 2013

Authors:

Kerstin Howe

Matthew D. Clark

Carlos Torroja

Abstract

A high-quality sequence assembly of the zebrafish genome reveals the largest gene set of any vertebrate and provides information on key genomic features, and comparison to the human reference genome shows that approximately 70% of human protein-coding genes have at least one clear zebrafish ortholog...

Subject

Zebrafish

Biology

Pseudogene

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