Delayed Cerebral Ischemia and Spreading Depolarization in Absence of Angiographic Vasospasm after Subarachnoid Hemorrhage

Woitzik, Johannes; P. Dreier, Jens; Hecht, Nils; Fiss, Ingo; Sandow, Nora; Major, Sebastian; K. L. Winkler, Maren; A. Dahlem, Yuliya; Manville, Jérôme; Diepers, Michael; Muench, Elke; Kasuya, Hidetoshi; Schmiedek, Peter; Vajkoczy, Peter

doi:10.1038/jcbfm.2011.169

Public

Delayed Cerebral Ischemia and Spreading Depolarization in Absence of Angiographic Vasospasm after Subarachnoid Hemorrhage

Published in Journal of Cerebral Blood Flow & Metabolism • Dec 7, 2011

Authors:

Johannes Woitzik

Jens P. Dreier

Nils Hecht

Abstract

It has been hypothesized that vasospasm is the prime mechanism of delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH). Recently, it was found that clusters of spreading depolarizations (SDs) are associated with DCI. Surgical placement of nicardipine prolonged-release impl...

Subject

Vasospasm

Subarachnoid hemorrhage

Medicine

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