A Randomized Trial of Maintenance Therapy for Vasculitis Associated with Antineutrophil Cytoplasmic Autoantibodies

Jayne, David; Rasmussen, Niels; Andrássy, K.; Bacon, Paul; Willem Cohen Tervaert, Jan; Dadonienė, Jolanta; Ekstrand, Agneta; Gaskin, Gill; Gregorini, Gina; de Groot, Kirsten; L. Gross, Wolfgang; Christiaan Hagen, E.; Mirapeix, E; Pettersson, E; E. H. Siegert, C.; Sinico, Alberto; Tesař, Vladimı́r; Westman, Kerstin; D. Pusey, Charles

doi:10.1056/nejmoa020286

Public

A Randomized Trial of Maintenance Therapy for Vasculitis Associated with Antineutrophil Cytoplasmic Autoantibodies

Published in New England Journal of Medicine • Jul 2, 2003

Authors:

David Jayne

Niels Rasmussen

K. Andrássy

Abstract

BACKGROUND: The primary systemic vasculitides usually associated with autoantibodies to neutrophil cytoplasmic antigens include Wegener's granulomatosis and microscopic polyangiitis. We investigated whether exposure to cyclophosphamide in patients with generalized vasculitis could be reduced by subs...

Subject

Medicine

Microscopic polyangiitis

Autoantibody

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